Gilbert’s syndrome (GS) was first reported in 1901 by Augustin Gilbert and is characterized by remittent unconjugated hyperbilirubinemia due to partial or complete absence of bilirubin uridine diphosphate (UDP)-glucuronosyl-transferase 1 (UGT1) activity1,2. Here, UGT1A1 is linked to Hyperbilirubinemia.