To determine whether cytotoxicity associated with GLO1 inhibition involved an apoptotic response, T98 and U87 GBM cells were treated with 30 μM p-BrBzGSH(Cp)2 for 24 h and DNA fragmentation was assayed by terminal deoxynucleotidyl transferase dUTP nick end-labeling (TUNEL). This evidence concerns the gene GLO1 and glioblastoma.