The Th-1-mediated cytokines production is markedly affected than Th-2-mediated cytokine release which promotes mucosal regulation of strongyloidiasis.[13] In addition, HIV infection causes elevated levels of IgE, eosinophils, and in turn suppresses the development of Strongyloides larvae in the gut necessary for autoinfection.[13,14] In contrast, cases of hyperinfection have been reported in HIV patients[46] and advances HIV illnesses.[47]. The gene discussed is NELFCD; the disease is strongyloidiasis.