In addition to the roles of RYBP in the particular types of cancer already discussed (Table 1), one study demonstrated histone deacetylase (HDAC)‐mediated down‐regulation of RYBP in v‐Fos‐transformed cells, while transient or stable re‐expression of RYBP in Fos‐transformed cells specifically promoted cell invasion/3‐D migration without affecting cell morphology, chemotaxis, migration and proliferation 69. Here, RYBP is linked to cancer.