CD4 and Autoimmunity: CD4+CD44highCD62Llow effector memory T cells (TEM) are, in contrast to naïve T cells, antigen‐primed and thus deliver T cell memory.20TEM are located in lymphoid and non‐lymphoid tissue and provide immediate local immune response.20, 21 With the presented work, we demonstrate a functional role of CD4+CD44high memory T cells in the pathogenesis of autoimmune‐related experimental pancreatitis.