SW480 and SW620 colon carcinoma cell lines are derived from primary and secondary tumours resected from the same patient.23 SW480 cells are mainly epithelial, whereas SW620 cells are mesenchymal.46, 47 The increase in the expression levels of Trx‐1, S100P and S100A4 were observed in SW620 cells compared with SW480 cells. This evidence concerns the gene S100A4 and neoplasm.