ESR1 and cancer: Sex steroids influence the development and progression of those mentioned cancers [7–12]; and it is generally accepted that the BPA effects in eukaryotic cells are mostly mediated by steroid receptors, including estrogen receptors (ER-α and -β), androgen receptor (AR), estrogen-related receptors (ERRs) and peroxisome proliferator-activated receptors (PPARs).