Immunohistochemical (IHC) analysis of these tissues revealed that Sur8 levels were higher in 9/13 (69.2%) CRC patient tumors compared with their adjacent normal tissue, whereas PKCα and PKCδ expression appeared lower in 11/13 (84.6%) and 8/13 (61.5%) of CRC tumors, respectively (Figure 6A-6D). This evidence concerns the gene SHOC2 and colorectal carcinoma.