PRMT1 and hepatocellular carcinoma: When the multivariate test was performed on the pooled cohort, the PRMT1 signature still retained its statistical significance for overall survival of HCC even after applying a variable selection procedure (HR = 1.612, 95% CI = 1.127 - 2.306, P = 0.009; Supplementary Table 3), demonstrating prognostic relevance of the PRMT1 signature as an independent risk factor for HCC.