Subsequently, we used flow cytometry to separated cell fractions from hormone treatment naïve (HNPC) and CRPC cells using CD49f and Trop2 antibodies and obtained luminal-like cells (CD49f-, Trop2+) and basal-like (CD49f+, Trop2+) cells from both HNPC and CRPC tumor cell cultures. This evidence concerns the gene TACSTD2 and neoplasm.