However, age, sex, tumor size, tumor location, histological type, tumor depth, lymph node metastasis, vascular invasion, perineural invasion, and preoperative and postoperative serum carcinoembryonic antigen (CEA) levels did not significantly differ between the patients with positive and negative EGFR expression. The gene discussed is EGFR; the disease is metastatic malignant neoplasm in the lymph nodes.