The mean methylation of the 1,214 aDNAm’s was similar by tumor subtype for Luminal A (mean beta 0.29), Luminal B (mean beta 0.31), and HER2 breast cancers (mean beta 0.28), but was statistically different for Basal (mean beta 0.23) (Figure 5B, Supplementary Figure 1B). The gene discussed is ERBB2; the disease is neoplasm.