CXCR2 and neoplasm: Consistently, the number of CXCR2+ MDSCs in 1g spleen and 1g primary tumor was also higher in mice with lymph node metastatic (32104.2 ± 3888.7 vs 22673.2 ± 1950.3 in 1g spleen, 8000.0 ± 1059.4 vs 4476.6 ± 1016.4 in 1g primary tumor) (Figure 2D, 2F).