Despite this and the absence of a requirement for excluding JAK2 V617F in diagnostic algorithms for neutropenia (Gong et al., 2013[3]; Palmblad et al., 2014[5]) an isolated neutropenia anecdotally appears to be a continual, if infrequent trigger for requesting JAK2 V617F mutation analysis. Here, JAK2 is linked to Decreased total neutrophil count.