Additional compelling results were detected for ARSA, SPSB2, CORO7 and PIGM. The ARSA gene encodes the arylsulfatase A, whose deficiency is characterised by decline in school performance, emergence of behavioural problems and neurologic symptoms, such as cerebellar ataxia, among others65. The gene discussed is SPSB2; the disease is aceruloplasminemia.