According to the results of pathway enrichment analysis, these DEPs could be enriched to the pentose phosphate pathway, glutathione metabolism, type II diabetes mellitus, insulin signaling pathway, protein processing in the endoplasmic reticulum, leukocyte transendothelial migration, complement and coagulation cascades, natural killer cell mediated cytotoxicity, B-cell receptor signaling pathway, T-cell receptor signaling pathway, and the NF-kappa B signaling pathway. Here, INS is linked to type 2 diabetes mellitus.