CD4 and neoplasm: In the 50% of untreated, 66.7% of BALB TB EV-treated, and 40% of BALB CD4 EV-treated B16F10 groups, or 50% of untreated and 60% of BALB CD4 EV-treated 4T1 groups, it was impossible to completely remove the tumours and these tumours invaded into the muscle or fatty layer (Fig. 4b; Table 1).