In detail, each GO term included genes essential for the control of the cell cycle at the G1/S and G2/M phase transitions, CDK1, CCNA2; a gene involved in DNA replication, MCM10; a gene with a crucial role in the control of cell proliferation, E2F1; histone gene cluster involved in regulation of chromosome structure or function and gene expression, HIST1H1A and HIST1H3B; and the BRCA1 gene that plays a role in maintaining genome stability and also acts as a tumor suppressor. This evidence concerns the gene E2F1 and neoplasm.