In the absence of sepsis, PCT levels of patients with metastatic tumor were significantly higher than those without metastasis, in contrast with CRP or leukocyte, where the increases in those markers were not statistically significant [13.6 mg/L (0.8–210.5) vs. 5.8 mg/L (0.5–209.8), p = 0.370, and 8860/μL (2930–24,910) vs. 7730/μL (1100–22,680), p = 0.629], respectively. This evidence concerns the gene CALCA and metastatic neoplasm.