ATG5 and metastatic malignant neoplasm in the lymph nodes: The results of multivariate Cox regression analysis validated axillary lymph node metastases (HR 2.055; 95% CI 1.190–3.547; P = 0.010), vascular invasion (HR 1.901; 95% CI 1.124–3.216; P = 0.017), and ATG5 rs473543 genotypes (HR 1.729; 95% CI 1.041–2.870; P = 0.034) as independent prognostic factors for DFS (Table 4).