BRAF and neoplasm: Whole-exome sequencing of resected tumour tissue from a smaller cohort of 109 PC patients reported that approximately 5% of cases contained 24 significantly mutated genes, some of which not only provided prognostic value in terms of disease pathology or patient survival (e.g., KRAS, RBM10), but also identified patients who may respond to targeted therapies (e.g., BRAF, PIK3CA) [24].