As a major compound of Shao Yao, PF efficiently alleviates oxidative damage in HUVECs via the ROS-HIF-1α/VEGF pathway, liver fibrosis by the HIF-1α/mTOR signaling pathway, non-alcoholic fatty liver disease through multiple signaling pathways, and inflammatory response in ulcerative colitis via inhibiting the MAPK/NF-κB pathway and apoptosis in mice [13,14,15,16]. This evidence concerns the gene HIF1A and Hepatic fibrosis.