The exact pathogenesis of ARVC is still unclear, but this involves a genetic factor.[34] Currently, the known genetic mutations associated with ARVC include PG, PKP2, DSP, DSC2, DSG2, TGFβ3, TMEM43, RYR2, TTN, and JUP.[35] Most of the patients reported had a family history and genetic tendency.[36] However, the patients included in this study had no family history of ARVC or SCD, and this may be associated with the absence of comprehensive clinical data. The gene discussed is TMEM43; the disease is Arrhythmogenic right ventricular dysplasia.