In several mouse models of atherosclerosis, treatment of mice with various pro-resolving ligands including annexin 1, Ac2-26, IL-10, resolvin D1 (RvD1), resolvin D2, or maresin 1 decreased lesional necrosis, suggesting improvements in efferocytosis by lesional phagocytes (90, 99, 100–102). Here, ANXA1 is linked to atherosclerosis.