Recognition by TLRs induced antiparasitic activity and the production of pro-inflammatory cytokines, such as IL-1, IL-6, TNF, IL-12 e IFN-γ (Akira and Sato, 2003; de Veer et al., 2003; Flandin et al., 2006; El Kasmi et al., 2008), which also could influence the rate of NOS2/ARG1 during infection. This evidence concerns the gene NOS2 and infection.