In univariate and multivariate logistic regression analyses, a neutrophil count above 9.14 × 109/L was independently associated with no-reflow after adjusting for age ≥ 65, male, smoking history, hypertension, diabetes, Killip classification ≥ 3, LAD as the IRA, neutrophil/lymphocyte ratio, cTNI, upfront intracoronary GPIIb/IIIa inhibitor administration, aspiration thrombectomy, platelet counts, WBC counts, HGB, time from symptom onset to reperfusion (>6 hours), multivessel disease, and initial TIMI flow grade (0-1). This evidence concerns the gene ITGA2B and glycogen storage disease VI.