The direct target genes for the Egfr/Raf pathway have not been identified; however, because compromised Egf signaling leads to defects in germline-soma interaction and overproliferation of spermatogonial cells, it is possible that the target genes regulate proper encapsulation of germ cells by cyst cells (Schulz et al. 2002; Sarkar et al. 2007). Here, EGFR is linked to cyst.