WLS and endometrial cancer: CGRRF1 expression is reduced in colon and endometrial cancer (Fig EV5G; TCGA, 2012), which correlates with increased Evi protein levels (Voloshanenko et al, 2013; Stewart et al, 2015) and a lack of transcriptional upregulation of Evi as assessed by TCGA expression data (Fig EV5H; TCGA, 2012).