In a prior series of 101 non-ccRCC pathologic specimens, positive PDL1 expression was noted in tumor-infiltrating mononuclear cells (TIMCs) in over half (56%) of the patients, and varied by histology from 36% in chromophobe RCC to 100% in collecting duct carcinoma. The gene discussed is CD274; the disease is nonpapillary renal cell carcinoma.