Among these, the prevalence of GDI is approximately 1 in 30,000 pregnancies, and patients with GDI are characterized in pregnancy by polyuria and polydipsia due to placental overproduction of vasopressinase, which is expressed in placental trophoblasts and degrades arginine vasopressin (AVP) [2, 3]. The gene discussed is AVP; the disease is Polyuria.