Among these, the prevalence of GDI is approximately 1 in 30,000 pregnancies, and patients with GDI are characterized in pregnancy by polyuria and polydipsia due to placental overproduction of vasopressinase, which is expressed in placental trophoblasts and degrades arginine vasopressin (AVP) [2, 3]. This evidence concerns the gene LNPEP and Gaucher disease type I.