Importantly, Schneider et al. used RS as an outcome measure in a clinical trial and found an improvement of RS in the N1/P2 complex in response to late vs. early sinusoidal tones in FXS participants after 3 months of minocycline treatment [15], pointing to the possibility of rescuing RS in humans as it was found in FMR1 KO mice [29]. Here, FMR1 is linked to fragile X syndrome.