SOX2 and head and neck squamous cell carcinoma: In addition, we identified regions harbouring oncogenes frequently activated in HNSCC as previously described [10, 32, 33, 39, 40]: 11q22 (BIRC2), 3q26 (SOX2, PIK3CA), 3q28 (TP63), 7p11 (EGFR), 17q12 (ERBB2), along with amplification of regions 8p11, 13q22 and 7q22.