REL and neoplasm: As expected, we found the activation of the TNF‐α/NF‐κB axis (Figs 2 and 4), and the knockdown of TNFR1, RelA, RelB, c‐Rel, and CUL4B showed similar effects on the proliferation, invasion, colony formation, and the in vivo tumor forming ability of cells (Figs 3 and 6).