Mice injected with U2OS‐RelA‐shRNA, U2OS‐RelB‐shRNA, and U2OS‐c‐Rel‐shRNA cells showed significantly slower tumor growth and decreased tumor volumes (51% reduction by day 25) compared with mice injected with U2OS‐control‐shRNA cells (Fig. 3D). This evidence concerns the gene RELA and neoplasm.