NFKB1 and Familial prostate cancer: Nuclear factor kappa‐light‐chain‐enhancer of activated B cells (NF‐κB), a transcription factor complex containing RelA, RelB, c‐Rel, p50, and p52 subunits, is constitutively active and translocated from the cytoplasm to the nucleus in many cancerous cells such as breast, colon, and prostate cancer cells (Gupta et al., 2010; Hoesel and Schmid, 2013).