The second study (NCT02220790) is called the BIOPIC study “BIOmarkers in Pediatric Invasive Candidiasis” and is prospectively enrolling 500 children at high-risk for developing invasive candidiasis and test four currently approved molecular assays for detection of Candida: (1→3)-β-d-glucan, mannan antigen, anti-mannan antibody, and the T2Candida platform. The gene discussed is PPIB; the disease is candidiasis.