While FISH results and CD5 positivity may be suggestive of a Richter's (large cell) transformation or chronic lymphocytic leukemia/small lymphocytic lymphoma, the overall morphologic and immunophenotypic findings, along with amplification of BCL2, were felt to be most consistent with diffuse large B‐cell lymphoma (DLBCL). Here, BCL2 is linked to diffuse large B-cell lymphoma.