CD5 and diffuse large B-cell lymphoma: While FISH results and CD5 positivity may be suggestive of a Richter's (large cell) transformation or chronic lymphocytic leukemia/small lymphocytic lymphoma, the overall morphologic and immunophenotypic findings, along with amplification of BCL2, were felt to be most consistent with diffuse large B‐cell lymphoma (DLBCL).