MARCO and tuberculosis: Polymorphisms in the macrophage receptor with collagenous structure (MARCO) gene, a receptor involved in M. tuberculosis phagocytosis (131), preferentially associated with Lineage 2 over Lineage 1 or 4, implying that the host MARCO genotypes may interact with M. tuberculosis of the Lineage 2 genotype to increase susceptibility to TB (132).