IL10 and allergic disease: With regard to allergic diseases, ex vivo models have shown that human tolerogenic IL-10 DCs from atopic donors suppressed TH2 immune responses by induction of FOXP3+ Tregs and dexamethasone-induced tolerogenic DCs activated IL-10 producing Tregs, specific for the latex Hev b 5 antigen, in rubber latex allergic patients (106, 107).