As for behavioral tests designed to mimic psychiatric symptoms, mice lacking TAAR1 showed no alteration in anxiety, stress response, and working memory, although significant impairment of sensorimotor gating functions could be observed (Wolinsky et al., 2007), which is postulated to be a hallmark of dopamine supersensitivity characteristic of positive psychotic symptoms (Thaker, 2008). This evidence concerns the gene TAAR1 and Anxiety.