Supported by grants from US National Institutes of Health (R01-S076843), Characterization of the Role of Cyclin G-associated Kinase in Parkinson Disease (R01-NS073947), Epigenetic Markers in Huntington's Disease Brain, (R01-NS088538) An IPSc based platform for functionally assessing genetic and environmental Risk in PD, (U24-NS072026) National Brain and Tissue Resource for Parkinson's Disease and Related Disorders, and the Jerry McDonald Huntington Disease Research Fund. The gene discussed is GAK; the disease is Huntington disease.