The results showed that OPC significantly improved alcohol-induced dyslipidemia and alleviated liver steatosis by reducing levels of serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), total triglyceride (TG), total cholesterol (TC), low-density cholesterol (LDL-c), and liver malondialdehyde (MDA) and increasing levels of serum high-density lipoprotein (HDL-c) and liver superoxide dismutase (SOD). This evidence concerns the gene GPT and metabolic syndrome.