FLT1 and neoplasm: In addition, Ye et al. reported an actively transcribed VEGFR1/FLT1 pseudogene (FLT1P1) that is transcribed bidirectionally in human colorectal cancer cells, and knockdown of its expression markedly inhibited CRC cells proliferation and tumor growth by inhibiting the VEGFR1 and VEGF-A expression through interacting with miR-520a in CRC cells [28].