Thus we next evaluated the expression levels of BOK protein and the key ER stress markers 78 kDa glucose-regulated protein/binding immunoglobulin protein (GRP78), heat shock protein 90 kDa beta member 1 (GRP94) and Calreticulin in fresh-frozen tumour resections of CRC patients. The gene discussed is HSP90B1; the disease is colorectal carcinoma.