With regard to the treatment of ischemic heart disease, especially myocardial infarction, VEGF has shown great potential for cardioprotection, including attenuating infarct size, preventing ventricular remodeling and improving cardiac function.3, 4, 31 In addition, it should be noted that VEGF gene‐based therapy for ischemic heart disease has been shown to avoid serious or lethal arrhythmias.8 This finding suggests that stabilizing cardiac electrical activity is also an important part of VEGF‐induced cardioprotection. The gene discussed is VEGFA; the disease is myocardial infarction.