Arterioles obtained from non‐DM subjects and treated with anti‐miR‐29b showed impaired Ach‐induced dilation (Fig 5J), similar to what was shown in Fig 2A. Simultaneous intraluminal transfection with Lypla1 siRNA significantly improved Ach‐induced dilation in these arterioles (Fig 5J). This evidence concerns the gene LYPLA1 and diabetes mellitus.