LGALS3 and infection: In this regards, there is evidence derived from infection by two bacterial pathogens, namely the Shigella flexneri, a rod-shaped, Gram-negative bacterium responsible for bacillary dysentary and the Listeria monocytogenes, a rod-shaped Garm-positive bacterium that causes severe meningitis and bacteriemia in immunocompromised hosts, that demonstrated that Gal-3 accumulates in structures in close proximity to phagosomes containing bacterial pathogens and are useful to detect membrane damage in bacteria’s vacuoles [366,367,368].