In a similar study by Wang and coworkers, autoantibodies against eight tumor-associated recombinant antigens (IMP1, p62, Koc, p53, c-myc, cyclin B1, survivin and p16) determined by ELISA and Western blot, showed 56.1% sensitivity for gastric cancer detection, at 86.2% specificity. Here, TP53 is linked to gastric cancer.