Moreover, topical application of GH within a short post-injury time frame showed an induction of neuroprotection after spinal cord injury (SCI) [65,66], and it is thought that this protective GH action is likely to also involve the expression of neurotrophins such as BDNF, GDNF, and IGF-I [67,68]. The gene discussed is IGF1; the disease is spinal cord injury.