In addition, we also found that the expression of PPARγ in both adipose and placenta tissues from GDM women was negatively correlated with trygylcerides levels, and positively correlated with LDL cholesterol and adiponectin levels, suggesting PPARγ may be involved the altered metabolism of lipid and lipoprotein in GDM women. The gene discussed is ADIPOQ; the disease is gestational diabetes.