For RFS, the prognostic factors on univariate analysis were tumor number (HR: 2.08; p < 0.001), tumor size (HR: 1.60; p = 0.002), CA19-9 (HR: 1.73; p < 0.001), CEA (HR: 2.08; p < 0.001), GGT (HR: 1.84; p < 0.001), adjunctive therapy (HR: 0.65; p < 0.001), vessel invasion (HR: 1.52; p < 0.001), alanine aminotransferase (ALT, HR: 1.41; p = 0.02), and aspartate aminotransferase (AST, HR: 1.36; p = 0.04). Here, CEACAM5 is linked to neoplasm.