MALT1 and cholangiocarcinoma: Moreover, univariate log-rank analysis of 100 post-hepatectomy patients with MF-CCA identified the following factors as adverse influences on OS (overall survival): the presence of symptoms, elevated alkaline phosphatase, decreased albumin, tumor size >5 cm, positive surgical margin and lymph node status, and MALT1 immunostaining (Supplementary Table 4).